GNOME is the ideal choice for almost any purpose:
GNOME is the desktop of choice for industry leaders like IBM, HP, and Sun. Governments in places as diverse as Kenosha, Wisconsin, in the US, Extremadura, Spain, and Beijing, China, have selected GNOME for their desktops. With a large number of users, and a wide range of vendors, you can be assured of availability and support for a long time to come.
GNOME for Business
Your business wants to cut costs and improve reliability, and GNOME is the obvious choice. GNOME's generous licensing means that you don't have to pay licensing fees or spend money keeping track of licenses, and you can build in-house software royalty-free, even if you choose not to release the source. GNOME also requires minimal training, and is easy to support, administer, and install, cutting your IT costs for rollout and maintenance.
GNOME for Home Users
GNOME is easy to use and easy to learn: the usability project team makes sure of it. GNOME has all the software you need every day: games, browser, email, office suite, and more. In addition, excellent Windows file compatibility means you can work with files that Windows users send you, and extensive manuals and help systems mean you're never without resources.
GNOME for Developers
GNOME gives developers the greatest licensing flexibility and the greatest variety of programming languages. In addition, you can even use Gtk+ on Windows as well as Unix and Linux systems.
Most GNOME libraries are available under the terms of the LGPL, which means you can develop GNOME software free of charge, no matter what license you use for your finished product. And because the GNOME object system is easy to bind to other languages, you can choose from a dozen popular development languages like Java, C#, Python, Perl, and of course plain old C and C++.
GNOME for the World
GNOME is available in your language. Many large software companies do not produce translations for smaller languages, but GNOME makes it easy for dozens of languages both large and small, including Azerbaijani, Arabic, Chinese, Hebrew, Spanish, and Swedish.
GNOME for People with Disabilities
If you have limited mobility or vision, then you'll be glad to hear that GNOME is serious about accessible software. GNOME works with screen readers, braille keyboards, and screen magnifiers, and meets accessibility requirements for many governments worldwide, including the US Department of Defense.
GNOME for System Administrators
Administrators choose GNOME because easy to use means easy to support, and because remote system administration cuts down on time spent pacing hallways and waiting in elevators. The GNOME System Administrations Guide has more information on how to manage a GNOME desktop deployment.